| Numerous treatments such as analgesic medications, muscle relaxants, antidepressants, and triptans had shown little or no effect. |
| Tricyclic antidepressants, including amitriptyline, can cause weight gain, drowsiness, and anticholinergic symptoms. |
| Many antidepressants inhibit serotonin or norepinephrine reuptake or both to achieve their clinical effect. |
| Anxiety, agitation, panic attacks, mania, and akathisia are some of the symptoms associated with use of antidepressants. |
| Finally, after an extended period, the positive effects of antidepressants can wear off. |
| Suddenly stopping antidepressants like Effexor, Paxil or Zoloft or nerve pills such as Ativan or Xanax can cause a range of reactions. |
