The stereochemistry of the model was checked and all residues found to be in allowed conformations. |
Together with the associated protein troponin, TM on actin can switch between two laterally shifted conformations. |
Then, we fix the adsorbed DNA molecules in their conformations thanks to uranyl acetate and we dry the sample using filter paper. |
For example, oxytocin and vasopressin have about a thousand different conformations in solution, all in dynamic equilibrium one with another. |
These simulation results suggest that the ensemble that minimizes them spans conformations with different degrees of nativeness. |
Therefore, the given stiffness values provide an effective description, obtained from sampling many different linker conformations. |